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MedChem
The inventor of Viagra (sildenafil), commonly known as "Weiguo." He has held executive positions at large pharmaceutical companies in the UK, US, and Switzerland (including GlaxoSmithKline, Pfizer, Merck, etc.), as well as at the biopharmaceutical company Ensemble Therapeutics. With over 35 years of experience in drug research and development, he has primarily been responsible for drug discovery and development, organic synthesis, and medicinal chemistry, covering multiple therapeutic areas including cardiovascular, inflammation, oncology, urology, antiviral, and antifungal fields.
He has made significant contributions to the discovery and development of several blockbuster drugs, particularly as the chemical project leader and inventor of sildenafil (ViagraTM). His technical contributions include establishing Pfizer's first combinatorial chemistry platform and developing DNA-encoded chemical libraries and advanced macrocyclic compounds during his tenure at Ensemble Therapeutics. He has proposed models that go beyond the "rule of 5" for more valuable drug candidates. With extensive experience in governing boards and leadership committees of large pharmaceutical companies and biotechnology advisory boards, he has created and fostered numerous collaborations between companies.
The inventor of Viagra (sildenafil), commonly known as "Weiguo." He has held executive positions at large pharmaceutical companies in the UK, US, and Switzerland (including GlaxoSmithKline, Pfizer, Merck, etc.), as well as at the biopharmaceutical company Ensemble Therapeutics. With over 35 years of experience in drug research and development, he has primarily been responsible for drug discovery and development, organic synthesis, and medicinal chemistry, covering multiple therapeutic areas including cardiovascular, inflammation, oncology, urology, antiviral, and antifungal fields.
He has made significant contributions to the discovery and development of several blockbuster drugs, particularly as the chemical project leader and inventor of sildenafil (ViagraTM). His technical contributions include establishing Pfizer's first combinatorial chemistry platform and developing DNA-encoded chemical libraries and advanced macrocyclic compounds during his tenure at Ensemble Therapeutics. He has proposed models that go beyond the "rule of 5" for more valuable drug candidates. With extensive experience in governing boards and leadership committees of large pharmaceutical companies and biotechnology advisory boards, he has created and fostered numerous collaborations between companies.

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